Design plasmids smarter.

A modular cloning system for your entire team.

ClutchBio is your organization’s DNA cloning core: we provide a modular plasmid design platform, comprehensive lab cloning services, and reusable DNA parts to improve turnaround time, reduce cost, and keep your team focused on what matters.

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See how it works

Our Approach

Our full suite of DNA design and cloning services includes specialized software, plasmid cloning services, and a biorepository. Together, these will improve your team’s productivity by removing cloning as the typical bottleneck for starting experiments and research projects.

Plasmid Design & Cloning Software

Collaborate effectively with our online software.

Increase your productivity, avoid institutional knowledge loss, and promote collaboration across your team.

Streamline your plasmid designs and cloning.

Easily create new constructs to enable plasmid assembly using your modular DNA toolkit. Prioritize speed or economy with build options.

Ask for technical and design support directly.

Communicate with us via a SlackConnect channel or video calls for assistance with software features.

Cloning Services

Receive sequence-verified plasmid DNA.

We ship purified, fully Nanopore-sequenced plasmid DNA.

Experience quick plasmid build times.

Our priority is turnaround time to help you advance your research. Use our online software to see your build progress.

Let us serve as your external cloning team.

Like an in-house team, we will work with you to troubleshoot cloning difficulties and provide useful feedback on builds.

Biorepository

Store parts in our biorepository for fast build times.

With your DNA toolkit on-site, we can start building your DNA assemblies as soon as you've submitted your order.

Re-use your DNA parts to save time and money.

A toolkit means faster build times, but also cost savings by not having to re-synthesize parts you repeatedly use.

Enjoy the benefits of long-term off-site storage.

Free your team from cumbersome sample handling. Send us your DNA for indefinite re-use in your biorepository.

Design with Genie

Our browser-based app allows high-throughput design of plasmid DNA parts and assemblies.

Learn about Genie

Plasmid Design

Use our Part Designer tool to easily add new parts to your organization’s DNA toolkit, and our Assembly Tool to design new Golden Gate assemblies using existing parts in your DNA toolkit.

Build Instructions

Genie provides detailed DNA build instructions as well as build progress to give you full transparency into the activities of your off-site cloning team.

Batch Ordering

Genie allows you to create a batch of plasmids and place an order for the batch that our team will fulfill. Our highest priority is turn-around time.

Collaboration

Genie allows all members of an organization to view and share their DNA toolkit, promoting collaboration, allowing discoverability, and facilitating project work.

Organization

Genie provides tools to aid in organization of plasmid and sequence information, including DNA feature annotation and projects.

Build with Toolkits

To achieve quick build times, we work with our clients to create a custom, modular DNA toolkit that encourages re-use of DNA parts.

Learn about toolkits

Custom modular DNA Toolkits

Build an entirely custom DNA toolkit to suit your organization's specific needs.

Designate functional categories for your different modular part types to standardize plasmid design across your organization

Take advantage of toolkits to enable efficient re-use of modular parts and facilitate onboarding of new team members

Streamline & Reuse

Streamline your plasmid designs and cloning using your DNA toolkit.

Use toolkits to support plasmid designs of different levels of complexity, from simple two-part assemblies to more advanced multi-part assemblies.

Use multiple assembly steps to achieve more complex plasmid designs containing operon or multi-gene configurations.

DNA Sourcing & Optimization

Vendor selection and ordering of synthesis-ready sequences.

Automatic redesign of difficult sequences to meet synthesis constraints (e.g., GC-rich regions, homopolymers).

Coordination with specialized synthesis providers for ordering of complex sequences.

See how it works

Iterate with a Biorepository

We understand the importance of moving quickly for research teams.

We prioritize quick turnaround times.

With our software platform, biorepository service, and Golden Gate cloning capabilities, we will get sequence-verified plasmid DNA in your hands as fast as possible. For plasmid designs that use existing parts in your DNA toolkit, we target build times of less than 1 week.

We deliver:

Purified plasmid DNA

Whole plasmid sequence verification

Saved DNA in Biorepository

Scientist to Scientist

See how leading labs are removing the cloning bottleneck to focus on the science.

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Andrew Ng

Principal Scientist, Genentech

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Andrew Ng

Principal Scientist, Genentech

Introductory Trial

We are confident that our DNA cloning tools and services will bring increased productivity and organization to your research team.

We are offering a paid, no-commitment trial period to allow you to experience how our services can improve your research and to provide you with accurate sense of our quick build times.

You will receive

Access to our online Genie application for plasmid and cloning design, for an unlimited number of users

Direct line of communication to us via Slack for software technical support, design assistance, and coordination

Onboarding to Golden Gate cloning and modular DNA toolkit system

Assistance with design of a custom modular system, including up to 4 hours of meetings and consulting work

Thirty sequence-verified plasmids, split across two batches, e.g. 15 basic part plasmids and 15 assembly plasmids

Request a Trial

Introductory Trial

We are confident that our DNA cloning tools and services will bring increased productivity and organization to your research team.

We are offering a paid, no-commitment trial period to allow you to experience how our services can improve your research and to provide you with accurate sense of our quick build times.

You will receive

Access to our online Genie application for plasmid and cloning design, for an unlimited number of users

Direct line of communication to us via Slack for software technical support, design assistance, and coordination

Onboarding to Golden Gate cloning and modular DNA toolkit system

Assistance with design of a custom modular system, including up to 4 hours of meetings and consulting work

Thirty sequence-verified plasmids, split across two batches, e.g. 15 basic part plasmids and 15 assembly plasmids

Request a Trial

Introductory Trial

We are confident that our DNA cloning tools and services will bring increased productivity and organization to your research team.

We are offering a paid, no-commitment trial period to allow you to experience how our services can improve your research and to provide you with accurate sense of our quick build times.